- MEN pathway Mutants
- tem1∆
- tem1∆ net1-ts
- tem1-ts GAL-CDC15
- tem1-ts multicopy CDC14
- cdc15∆
- cdc15-ts multicopy TEM1
- cdc15-ts multicopy CDC14
- cdc15∆ net1-ts
- cdc15∆ net1-ts cdh1∆
- TAB6-1 cdc15∆
- GAL-TEM1
- mad2∆ GAL-TEM1 in nocodazole
- Multi-copy CDC15
tem1∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ka15"=0.002 (=ka15').
Length of G1 phase: 33.6 min.
Arrest: Telophase arrest.
Experiments:
Shirayama, M., Matsui, Y. and Toh-e, A. (1994b). The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase. Mol. Cell. Biol. 14:7476-7482.
[Abstract] [Article]
[Abstract] [Article]
Jaspersen, S.L., Charles, J.F., Tinker-Kulberg, R.L., and Morgan, D.O. (1998). A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae. Mol. Biol. Cell 9:2803-2817.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Telophase arrest.
Comments:
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